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A week of mindfulness, and the question it leaves open

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Twenty-one randomised trials or meta-analyses in psychotherapy entered PubMed since 28 July. Three of the four studies retained here evaluate acceptance- or mindfulness-based interventions, and all three conclude favourably — yet the broadest meta-analysis of the four rates its own certainty of evidence as low to very low. The Without Borders section recalls where the figures are, by contrast, solid.

Research

Working on emotion regulation adds something to CBT for alcohol use disorder

K. S. Knapp, B. K. Linn, J. Zhao et al.Alcohol, Clinical & Experimental Research · 2026 · essai randomisé de phase II, 194 patients

One hundred and ninety-four adults with moderate-to-severe alcohol use disorder underwent twelve weeks of outpatient treatment, with CBT augmented either by an emotion-regulation module or by an active health-and-lifestyles module. The emotion-regulation group achieved a higher percentage of days abstinent at every follow-up out to twelve months, with no difference in heavy drinking days. The effect ran partly through better adaptive coping in the very first week of treatment — an early mediator, and the only one detected.

Source10.1111/acer.70350

Chronic pain: psychological flexibility improves, but the certainty of evidence is low

J. P. Sanabria-Mazo, C. Rodríguez-Freire, E. Royuela-Colomer et al.European Journal of Pain · 2026 · revue systématique et méta-analyse, 60 essais, 6 692 participants

Sixty randomised trials pooling 6,692 adults with chronic pain. Acceptance- and mindfulness-based interventions improve global psychological flexibility (g = 0.35 to 0.69) and acceptance (0.41 to 0.77), at both short and long follow-up; committed action and values do not move significantly. The authors report substantial heterogeneity, high risk of bias in most trials, and themselves rate the certainty of evidence as low to very low — effects are also larger when the comparator is inactive.

Source10.1002/ejp.70342

Non-suicidal self-injury in hospitalised adolescents: four weeks of mindfulness-based cognitive therapy

J. Xie, L. Li, X. Liu et al.Psychological Medicine · 2026 · essai randomisé en simple aveugle, 94 adolescents hospitalisés · Chine

Ninety-four adolescents hospitalised for depressive disorder and engaging in non-suicidal self-injury were allocated to adolescent mindfulness-based cognitive therapy added to treatment as usual, or to treatment as usual alone. Self-injury severity differed significantly between groups at four weeks, on both intention-to-treat and per-protocol analysis, and the reduction held at one-month follow-up. Secondary gains covered mindful awareness and non-reactivity, emotion regulation, rumination and depressive symptoms.

Source10.1017/S0033291726104735

What does an app-delivered acceptance therapy work through? Four processes out of six

C. Zhao, Z. Ren, M. E. Levin et al.European Journal of Psychotraumatology · 2026 · analyse secondaire d'un essai randomisé, 145 participants · Chine

Secondary analysis of a Chinese randomised trial comparing a mobile app-delivered acceptance and commitment therapy programme (78 participants) with a waitlist (67), in people with post-traumatic stress disorder. Of the six components of psychological flexibility, four — acceptance, self-as-context, cognitive defusion, committed action — fully mediated the effect on symptoms; present-moment awareness and valued living mediated it only partly. This is a mechanism study, not an efficacy one: it says where the effect runs, not how large it is.

Source10.1080/20008066.2026.2702140

Without borders

Psychological care delivered where there are no psychotherapists: task-sharing, lay health workers, cultural adaptation. Humanitarian medicine established this ground elsewhere; psychotherapy is following.

Psychological interventions delivered by non-specialists: the reference figures

E. Karyotaki, R. Araya, R. C. Kessler et al.JAMA Psychiatry · 2022 · méta-analyse sur données individuelles, 11 essais, 4 145 patients · Pays à revenu faible et intermédiaire

Eleven randomised trials conducted in low- and middle-income countries, reanalysed patient by patient. Psychological interventions delivered by workers with no prior clinical training reduce depression severity more than control conditions (g = 0.32), and roughly double the odds of response (odds ratio 2.11) and of remission (1.87). This is the statistical foundation on which task-sharing in mental health rests; heterogeneity across trials reaches 74%.

Source10.1001/jamapsychiatry.2022.0301

Zimbabwe's Friendship Bench, and what it cannot do

J. Patena, D. Adenikinju, P. Lanka et al.Global Mental Health · 2025 · revue systématique, 7 études sur 641 articles criblés · Zimbabwe

The programme entrusts problem-solving therapy to lay health workers, on a bench set beside the clinic. Six hundred and forty-one articles screened, seven retained, all Zimbabwean: the review concludes the approach is acceptable, appropriate and feasible for narrowing the treatment gap in common mental disorders, carried by cultural adaptability and the trust placed in lay workers. The limits are named plainly: no downstream mental health system, inability to handle severe conditions, stigma.

Source10.1017/gmh.2025.10025

In Kerala, door-to-door students as the first link in case-finding

S. M. Devassy, L. Scaria, N. CheguveraPilot and Feasibility Studies · 2022 · étude de faisabilité, 549 habitants · Inde · Kerala

Five hundred and forty-nine residents of three localities were interviewed at home by students trained to detect depression and suicidality. Eleven per cent had mild depression, 8.4% moderate and 4.9% severe; suicidal thoughts affected 6.9% of respondents. Twenty-seven people were referred to high-intensity care and one hundred and thirty-five to a low-intensity intervention; the model is to be tested across five panchayats before any nationwide extension.

Source10.1186/s40814-022-01159-0

Compiled from PubMed (National Library of Medicine). Each item links to its PubMed record and carries its DOI. LogiMind is not affiliated with the NLM.

These are summaries of published research, with a link to each source. They are not clinical advice and do not replace consultation with a qualified professional.